Our research focuses on the molecular biology of host-microbe interactions, microbial pathogenesis, and hormone signaling in disease.
April 16, 2025
Soo passed her prelim, with a proposal focused on the effectors that bacteria use to infect and proliferate in plants.
February 24, 2025
Annie completed here PhD at Johns-Hopkins studying in Rachel Green's lab.
February 18, 2025
After many years of productive research in the He Lab, Brad was hired to a new position at Sandia National Labs in New Mexico!
Philip Versluis was awarded a Hargitt Fellowship from the Duke Biology Department. He aims to understand the molecular mechanisms of the immune master transcription factors CBP60g and SARD1 and rationally engineer them to yield more robust immunity.
Sheng Yang He made the Clarivate Highly Cited Researchers list for 2024! Seee the full list here: https://clarivate.com/highly-cited-researchers/
Sept 20, 2024: Chi Kuan and the lab celebrated her passing the prelim exam and becoming a PhD Candidate!
Sept 16, 2024: Yu Ti Cheng's paper on the microbiome and autoimmunity is out in Nature Plants, and is featured in Duke Today.
August 12th, 2024: He lab celebrated the retirement of Dr. Kinya Nomura, a long-standing lab member since 2000. Dr. Nomura was instrumental in many signature research projects of the He lab over a period of 24 years, and helped many lab members launch their careers. He will be missed!
Sheng Yang and the lab received a second renewal of HHMI funding for 7 years!
The newly minted PhD candidates celebrated by sharing a bottle of bubbly with the lab after passing their prelim exams.
Clarivate, an analytics firm, included Sheng Yang and other Duke researchers on the list of most-cited scholars this year.
Nomura et al. 2023 was written up for a popular science audience by Kamal Nahas - A New Drug Fixes a Leak caused by Bacteria
Prof. Sheng Yang He travelled to Lyon, France, to present at the International Congress of Plant Pathology.
Read the article here.
Congratulations as we send off Dr. Kim to start his new position at POSTECH Department of Life Sciences, South Korea!
Read more here about talk at ICAR and the Plant Microbioe Symposium!
See the list of highly cited researchers here.
Shanice will use this fellowship support to investigate tritrophic interactions between the plant host, the microbiome and pathogens. The Hanna Gray Fellowship provides both postdoctoral support and funds for startup as a PI when she establishes her own lab! Read more about Shanice and her cohort here!
André has recently accepted a position at WCU! He will be dearly missed by all and we wish him the best of luck in the next phase of his career!
Li accepted a position in the Department of Biology and Basic Medial Sciences at Soochow University in China! She will be dearly missed by all and we wish her the best of luck in the next phase of her career!
Sheng Yang was recently interviewed on Science Friday in regard to our lab's recent Nature publication Increasing the resilience of plant immunity to a warming climate. Click here to listen!
Hannah's NSF PRFB proposal titled "Understanding microbiome impact on plant performance in a warming climate" was recently funded and will address knowledge gaps in “temperature-microbiome-plant” triangular interactions to reveal underlying principles of emergent plant and microbiome function(s) in warming conditions. Congrats Hannah!
Paula has recently joined our lab as a Ph.D. student in the Biology Department here at Duke University. She is interested in unraveling the interplay between biotic and abiotic stress pathways, particularly how salt stress can modulate plant-microbe interactions. Welcome Paula!
See the list of highly cited researchers here.
Shanice’s graduate work focused on understanding the mechanisms by which free-swimming bacteria sense surface contact and transition to surface attachment (biofilm formation). She determined a mechanism by which cysteines in a type 4 pili cell-surface-associated protein senses surface contact and initiates a signal transduction cascade to regulate intracellular levels of the second messenger molecule c-di-GMP. In the He lab, Shanice is investigating how pathogenicity affects changes in the plant microbiome and how such changes contribute to disease development.
Brad successfully defended his dissertation work this past November! Congratulations, Brad!
Tim joined the lab in October 2020 and has made several important contributions to microbiome and pathogenesis related projects in the lab. On top of being a brilliant scientist, Tim has been a wonderful colleague and lab citizen. We wish you the best of luck in your future endeavor!
Hannah's graduate work at Duke focused on the roles bacterial outer membrane vesicles play in plant systems. She found that these nanoscale proteoliposomes elicit immune responses in plants that can protect against future pathogen challenge. In the He lab, Hannah is looking forward to uncovering how temperature impacts the plant microbiome structure and function.
During his graduate studies at NYU, Comzit worked with social insects and used the Indian jumping ant as a model of study. Division of labor is crucial and stable in social insect communities; however, in jumping ants, caste switching can occur in a queenless colony. His research provided insight into the mechanisms underlying these unusual changes in ant behavior and longevity. He will be making a transition from the animal to the plant kingdom to figure out how humidity influences plant growth and disease susceptibility.
Learn more about Rich's fellowship here!