Recent Publications

                Plants control microbiome diversity inside leaves to promote health

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Pathogenic bacteria target plant plasmodesmata to colonize and invade surrounding tissues.  Aung, K., et al. (2019) The Plant Cell

Challenging battles of plants with phloem-feeding insects and prokaryotic pathogens. Jiang Y, et al. (2019) PNAS

Plant-Microbe Interactions Facing Environmental Challenge. Cheng Y, et al. (2019) Cell Host and Microbe

An important role of L-fucose biosynthesis and protein fucosylation genes in Arabidopsis immunity. Zhang L, et al. (2019) New Phytologist

Plant–pathogen warfare under changing climate conditionsVelásquez AC, et al. (2018) Current Biology

Salicylic acid-independent role of NPR1 is required for protection from proteotoxic stress in the plant endoplasmic reticulum. Lai YS, et al. (2018) PNAS

Transcriptome landscape of a bacterial pathogen under plant immunity. Nobori T, et al. (2018) PNAS

Pseudomonas syringae: what it takes to be a pathogen. Xin XF, Kvitko B, He SY. (2018) Nat. Rev. Microbiol.

The role of water in plant-microbe interactions. Aung K., et al. (2017) Plant Journal

Dual impact of elevated temperature on plant defence and and bacterial virulence in Arabidopsis. Huot B., et al. (2017) Nature Communications

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Effector translocation: cya reporter assay. Chakravarthy S, et al. (2017) Methods Mol. Biol.

Leucine-rich-repeat-containing variable lymphocyte receptors as modules to target plant-expressed proteins. Velásquez AC, et al. (2017) Plant Methods

Diverse mechanisms of resistance to Pseudomonas syringae in a thousand natural accessions of Arabidopsis thaliana. Velásquez AC, et al. (2017) New Phytologist

Stomatal defense a decade later. Melotto M, et al. (2017) Plant Physiology

Jasmonate signaling and manipulation by pathogens and insects. Zhang L, et al. (2017) J. Exp. Bot.

Structural insights into alternative splicing-mediated desensitization of jasmonate signaling. Zhang F, et al. (2017) PNAS

Bacteria establish an aqueous living space in plants crucial for virulence. Xin XF, et al. (2016) Nature

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                Mis-placed Congeniality: When Pathogens Ask Their Plant Hosts for Another Drink

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Allelic diversity in an NLR gene BPH9 enables rice to combat planthopper variation. Zhao Y, et al. (2016) PNAS

Salicylic acid receptors activate jasmonic acid signalling through a non-canonical pathway to promote effector-triggered immunity. Liu L, et al. (2016) Nature Communications

Pseudomonas syringae type III effector HopG1 induces actin remodeling to promote symptom development and susceptibility during infection. Shimono M, et al. (2016) Plant Physiology

Alternative splicing of rice WRKY62 and WRKY76 transcription factor genes in pathogen defense. Liu J, et al. (2016) Plant Physiology

Host target modification as a strategy to counter pathogen hijacking of the jasmonate hormone receptor. Zhang L, et al. (2015) PNAS

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Structural basis of JAZ-mediated repression of MYC transcription factors in jasmonate signaling. Zhang F, et al. (2015) Nature

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A host plant genome aftercentury-long endophyte infection. Guo L, et. al. (2015) The Plant Journal

Pseudomonas syringae effector AvrE localizes to the host plasma membrane and down-regulates the expression of the NDR/HIN1-like 13 gene required for antibacterial immunity in Arabidopsis. Xin XF, et al. (2015) Plant Physiology

Growth-defense tradeoffs in plants: a balancing act to optimize fitness. Huot B, et al. (2014) Molecular Plant

A bacterial tyrosine phosphatase inhibits plant pattern recognition receptor activation. Macho AP, et al. (2014) Science

                Cell: Uninvited Guests

Fine-scale temporal dynamics of growth and photosynthesis suppression by jasmonate signaling. Attaran E, et al. (2014) Plant Physiology

The bacterial effector HopM1 suppresses PAMP-triggered oxidative burst and stomatal immunity. Lozano-Durán R, et al. (2014) New Phytology

Pseudomonas syringae pv. tomato DC3000 as a model for probing disease susceptibility and jasmonate signaling in plants. Xin, XF and He, SY (2013) Annual Review of Phytopathology

Molecular evidence for dual pyrethroid-receptor sites on a mosquito sodium channel. Du Y, et al. (2013) PNAS

Pseudomonas syringae infection assays in Arabidopsis. Yao J, Withers J, He SY (2013) Methods in Molecular Biology

Induction and suppression of PEN3 focal accumulation during Pseudomonas syringae pv. tomato DC3000 infection of Arabidopsis. Xin XF, et al. (2013) Molecular Plant-Microbe Interactions

Negative feedback control of jasmonate signaling by an alternative splice variant of JAZ10. Moreno JE, et al. (2013) Plant Physiology

Bacterial effector activates jasmonate signaling by directly targeting JAZ transcriptional repressors. Jiang S, et al. (2013) PLoS Pathogens

The Long-Sought-After Salicylic Acid Receptors. Attaran E & He SY (2012) Molecular Plant

Transcription factor-dependent nuclear localization of a transcriptional repressor in jasmonate hormone signaling. Withers J, et al. (2012) PNAS

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Plant hormone jasmonate prioritizes defense over growth by interfering with gibberellin signaling cascade. Yang DL, et al. (2012) PNAS

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Coronatine Promotes Pseudomonas syringae Virulence in Plants by Activating a Signaling Cascade that Inhibits Salicylic Acid Accumulation. Zheng XY, et al. (2012) Cell and Host Microbe 

Localization of DIR1 at the tissue, cellular and subcellular levels during systemic acquired resistance in Arabidopsis using DIR1:GUS and DIR1:EGFP reporters. Champigny MJ, et al. (2011) BMC Plant Biology

Genome sequence of the plant-pathogenic bacterium Dickeya dadantii 3937. Glasner JD, et al. (2011) Journal of Bacteriology 

A critical role of STAYGREEN/NON-YELLOWING Mendel's locus in disease symptom development during Pseudomonas syringae pv. tomato infection of Arabidopsis. Mecey C, et al. (2011) Plant Physiology

Effector-triggered immunity blocks pathogen degradation of an immunity-associated vesicle traffic regulator in Arabidopsis. Nomura K, et al. (2011) PNAS

A genetic screen reveals Arabidopsis stomatal and/or apoplastic defenses against Pseudomonas syringae pv. tomato DC3000. Zeng W, et al. (2011) PLoS Pathogen

Previous Years - Select Publications

Jasmonate perception by inositol-phosphate-potentiated COI1-JAZ co-receptor. Sheard LB, et al. (2010) Nature

Type III secretion in plant pathogenic bacteria. Büttner, D & He, SY. (2009) Plant Physiology

A family of conserved bacterial effectors inhibits salicylic acid-mediated basal immunity and promotes disease necrosis in Arabidopsis. DebRoy S, et al. (2004) Proceedings of the National Academy of Sciences USA

A Pseudomonas syringae type III effector suppresses cell wall-based extracellular defense in susceptible Arabidopsis plants. Hauck P, et al. (2003) Proceedings of the National Academy of Sciences USA

Role of the Hrp pilus in type III secretion in Pseudomonas syringae. Jin Q-L. and He SY. (2001) Science

The Arabidopsis thaliana-Pseudomonas syringae Interaction. Katagiri F, et al. (2002) The Arabidopsis Book, eds. C.R. Somerville and E.M. Meyerowitz, American Society of Plant Biologists, Rockville, MD.

The gene coding for the structural protein of the Hrp pilus is required for type III secretion of Hrp and Avr proteins in Pseudomonas syringae pv. tomato. Wei W, et al. (2000) Proceedings of the National Academy of Sciences USA

Hrp pilus: An hrp-dependent bacterial surface appendage produced by Pseudomonas syringae pv. tomato DC3000. Roine E, et al. (1997) Proceedings of the National Academy of Sciences USA

Expression of the Pseudomonas syringae avirulence protein AvrB in plant cells alleviates its dependence on the hypersensitive response and pathogenicity (Hrp) secretion system in eliciting genotype-specific hypersensitive cell death. Gopalan S, et al. (1996) Plant Cell

Pseudomonas syringae pv. syringae harpinPss: a protein that is secreted via the Hrp pathway and elicits the hypersensitive response in plants. He SY, et al. (1993) Cell

Harpin, elicitor of the hypersensitive response produced by the plant pathogen Erwinia amylovora. Wei Z-M., et al. (1992) Science

Cloned out genes from Erwinia chrysanthemi EC16 enable Escherichia coli strains to selectively secrete a diverse family of heterologous proteins to its milieu. He SY, et al. (1991) Proceedings of the National Academy of Sciences USA


US 20170215351 A1
Methods and Apparatus for Gnotobiotic Plant Growth (2017) James Kremer, James Tiedje and Sheng Yang He

US PPA 62/413850
Structurally modified COI1 (2016) Sheng Yang He, Li Zhang et al.

US 8058507 B2

HOPM1 mediated disease resistance to Pseudomonas syringae in Arabidopsis (2011) Sheng Yang He and Kinya Nomura

US 9068192 B2
Compositions and Methods for Conversion of Aldehydes to Alkanes (2011) Weiqing Zeng and Sheng Yang He

US 6342654 B1
Broad-spectrum disease resistance conferred by expression of the Pseudomonas syringae hrmA gene in plants (2001) Qingshun Li, Songhai Shen,  Arthur Hunt and Sheng Yang He

US 5849868 A
Elicitor of the hypersensitive response in plants (1998) Steve Beer et al.
This patent has led to the development of the disease control product “MESSENGERTM” sold by Eden Bioscience Corp.

US 5708139 A
Pseudomonas syringae pv. syringae HrpZ gene (1997) Alan Collmer and Sheng Yang He