Publications
Recent Publications
Roles of microbiota in autoimmunity in Arabidopsis leaves. Chen et al. (2024) Nature Plants
New coverage:
Duke Today - Crop Diseases, Spoilage Can Hurt the Food Supply. Could Plant Prebiotics Help?
Nature Plants Research Briefing - Unbalanced leaf microbiota can cause autoimmunity in plants
Small proteins modulate ion-channel-like ACD6 to regulate immunity in Arabidopsis thaliana. Chen et al. (2023) Molecular Cell
Bacterial pathogens deliver water- and solute-permeable channels to plant cells. Nomura, et al. (2023) Nature
News coverage and commentary:
Duke Today - Mysterious Family of Microbial Proteins Hijack Crops’ Cellular Plumbing
Nature News & Views - Bacteria deliver water channels to infect plants
HHMI News - How Tubular Bacterial Weapons Compromise Plant Cells to Cause Disease
A critical role of a eubiotic microbiota in gating proper immunocompetence in Arabidopsis. Paasch, et al. (2023) Nature Plants
Plants target gut microbes to reduce insect herbivore damage. McMillan (2023) PNAS. Commentary.
NLR surveillance of pathogen interference with hormone receptors induces immunity. Chen, et al. (2022) Nature
Increasing the resilience of plant immunity to a warming climate. Kim and Castroverde, et al. (2022) Nature
Check out these commentaries and other articles regarding this manuscript!
Sustaining plant immunity in rising temperature (Cell Research)
Shedding light on immune suppression at high temperature (Trends in Microbiology)
Climate Change Breaks Plant Immune Systems. Can They Be Rebooted? (WIRED)
Can Genetic Modification Help Plants Survive Climate Change? (Science Friday interview with Sheng Yang)
Climate change is making plants more vulnerable to disease. New research could help them fight back (Duke Today)
A Souped-Up Gene Promoter Stops Heat from Sapping Plant Defenses (HHMI News)
Growth-defense tradeoffs in plants. He, et al. (2022) Current Biology
Ectopic expression of OsJAZs Alters Plant Defense and Development. Sun, et al. (2022) International Journal Molecular Sciences
The bacterial effector AvrRxo1 inhibits vitamin B6 biosynthesis to promote infection in rice. Liu, et al. (2022) Plant Communications
Phytocytokine signaling reopens stomata in plant immunity and water loss. Liu, et al. (2022) Nature
Shared in plant population and transcriptomic features of nonpathogenic members of endophytic phyllosphere microbiota. Velásquez, et al. (2022) PNAS
An MPK-MAPK protein phosphorylation cascade controls vascular immunity in plants. Lin, et al. (2022) Science Advances
Evolutionarily conserved bacterial effectors hijack abscisic acid signaling to establish an aqueous environment in the apoplast. Roussin-Léveillée, et al. (2022) Cell Host & Microbe
Oxicam-type non-steroidal anti-inflammatory drugs inhibit NPR1-mediated salicylic acid pathway. Ishihama, et al. (2021) Nature Communications
A bacterial kinase phosphorylates OSK1 to suppress stomatal immunity in rice. Wang, et al. (2021) Nature Communications
FERONIA restricts Pseudomonas in the rhizosphere microbiome via regulation of reactive oxygen species. Song, et al. (2021) Nature Plants
Peat-based gnotobiotic plant growth systems for Arabidopsis microbiome research. Kremer, Sohrabi and Paasch, el al. (2021) Nature Protocols
Toward understanding microbiota homeostasis in the plant kingdom. Paasch and He. (2021) PLOS Pathogens
Featured In: Plant immunity unified
Crops of the future: building a climate-resilient immune system. Kim, et al. (2021) Current Opinion in Plant Biology
Arabidopsis calcium-dependent kinase 3 regulates actin cytoskeleton organization and immunity. Lu, et al. (2020) Nature Communications
Citrus CsACD2 is a target of Candidatus Liberibacter asiaticus in Huanglongbing disease. Pang and Zhang, et al. (2020) Plant Physiology
Featured In: Plants control microbiome diversity inside leaves to promote health
Nature Plants Research Highlight: Phyllosphere dysbiosis
PLOS Featured Microbiome Research Article
Current Biology Featured Article: Life on Plants
Western Producer Featured Article:Plants select which microbes have a change to live with them
Trends in Plant Science Spotlight: Linking Phyllosphere Microbiome to Plant Health
The Conversation: When plants and their microbes are not in sync, the results can be disasterous
Diversity, function and regulation of cell surface and intracellular immune receptors in solanaceae. Kim, JH., et al. (2020) Plant Innate Immunity
Pathogenic bacteria target plant plasmodesmata to colonize and invade surrounding tissues. Aung, K., et al. (2019) The Plant Cell
Challenging battles of plants with phloem-feeding insects and prokaryotic pathogens. Jiang Y, et al. (2019) PNAS
Plant-Microbe Interactions Facing Environmental Challenge. Cheng Y, et al. (2019) Cell Host and Microbe
An important role of L-fucose biosynthesis and protein fucosylation genes in Arabidopsis immunity. Zhang L, et al. (2019) New Phytologist
Plant–pathogen warfare under changing climate conditions. Velásquez AC, et al. (2018) Current Biology
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Pseudomonas syringae: what it takes to be a pathogen. Xin XF, Kvitko B, He SY. (2018) Nat. Rev. Microbiol.
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Dual impact of elevated temperature on plant defence and and bacterial virulence in Arabidopsis. Huot B., et al. (2017) Nature Communications
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Leucine-rich-repeat-containing variable lymphocyte receptors as modules to target plant-expressed proteins. Velásquez AC, et al. (2017) Plant Methods
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Diverse mechanisms of resistance to Pseudomonas syringae in a thousand natural accessions of Arabidopsis thaliana. Velásquez AC, et al. (2017) New Phytologist
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Structural insights into alternative splicing-mediated desensitization of jasmonate signaling. Zhang F, et al. (2017) PNAS
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Allelic diversity in an NLR gene BPH9 enables rice to combat planthopper variation. Zhao Y, et al. (2016) PNAS
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Salicylic acid receptors activate jasmonic acid signalling through a non-canonical pathway to promote effector-triggered immunity. Liu L, et al. (2016) Nature Communications
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Pseudomonas syringae type III effector HopG1 induces actin remodeling to promote symptom development and susceptibility during infection. Shimono M, et al. (2016) Plant Physiology
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Alternative splicing of rice WRKY62 and WRKY76 transcription factor genes in pathogen defense. Liu J, et al. (2016) Plant Physiology
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Structural basis of JAZ-mediated repression of MYC transcription factors in jasmonate signaling. Zhang F, et al. (2015) Nature
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Growth-defense tradeoffs in plants: a balancing act to optimize fitness. Huot B, et al. (2014) Molecular Plant
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A bacterial tyrosine phosphatase inhibits plant pattern recognition receptor activation. Macho AP, et al. (2014)Science
Featured In: Cell: Uninvited Guests
Fine-scale temporal dynamics of growth and photosynthesis suppression by jasmonate signaling. Attaran E, et al. (2014) Plant Physiology
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The bacterial effector HopM1 suppresses PAMP-triggered oxidative burst and stomatal immunity. Lozano-Durán R, et al. (2014) New Phytology
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Pseudomonas syringae pv. tomato DC3000 as a model for probing disease susceptibility and jasmonate signaling in plants. Xin, XF and He, SY (2013) Annual Review of Phytopathology
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Molecular evidence for dual pyrethroid-receptor sites on a mosquito sodium channel. Du Y, et al. (2013) PNAS
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Pseudomonas syringae infection assays in Arabidopsis. Yao J, Withers J, He SY (2013) Methods in Molecular Biology
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Induction and suppression of PEN3 focal accumulation during Pseudomonas syringae pv. tomato DC3000 infection of Arabidopsis. Xin XF, et al. (2013) Molecular Plant-Microbe Interactions
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Negative feedback control of jasmonate signaling by an alternative splice variant of JAZ10. Moreno JE, et al. (2013) Plant Physiology
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Bacterial effector activates jasmonate signaling by directly targeting JAZ transcriptional repressors. Jiang S, et al. (2013) PLoS Pathogens
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Transcription factor-dependent nuclear localization of a transcriptional repressor in jasmonate hormone signaling. Withers J, et al. (2012) PNAS
Plant hormone jasmonate prioritizes defense over growth by interfering with gibberellin signaling cascade.Yang DL, et al. (2012) PNAS
Featured In: MSU Today News Article
Coronatine Promotes Pseudomonas syringae Virulence in Plants by Activating a Signaling Cascade that Inhibits Salicylic Acid Accumulation. Zheng XY, et al. (2012) Cell and Host Microbe
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Localization of DIR1 at the tissue, cellular and subcellular levels during systemic acquired resistance in Arabidopsis using DIR1:GUS and DIR1:EGFP reporters. Champigny MJ, et al. (2011) BMC Plant Biology
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Genome sequence of the plant-pathogenic bacterium Dickeya dadantii 3937. Glasner JD, et al. (2011) Journal of Bacteriology
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A critical role of STAYGREEN/NON-YELLOWING Mendel's locus in disease symptom development during Pseudomonas syringae pv. tomato infection of Arabidopsis. Mecey C, et al. (2011) Plant Physiology
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A genetic screen reveals Arabidopsis stomatal and/or apoplastic defenses against Pseudomonas syringae pv. tomato DC3000. Zeng W, et al. (2011) PLoS Pathogen
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Previous Years - Select Publications
Jasmonate perception by inositol-phosphate-potentiated COI1-JAZ co-receptor. Sheard LB, et al. (2010) Nature
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COI1 is a critical component of a receptor for jasmonate and the bacterial virulence factor coronatine. Katsir L, et al. (2008) Proceedings of the National Academy of Sciences USA
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Role of stomata in plant innate immunity and foliar bacterial diseases. Melotto M, et al. (2008) Annual Reviews Phytopathology
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Suppression of the MicroRNA pathway by bacterial effector proteins. Navarro L, et al. (2008) Science
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JAZ repressor proteins are targets of the SCFCOI1 complex during jasmonate signalling. Thines B, et al. (2007) Nature
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A bacterial virulence protein suppresses host innate immunity to cause plant disease. Nomura K, et al. (2006) Science
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Suppression of host defense in compatible plant-Pseudomonas syringae interactions. Nomura K, et al (2005) Current Opinion Plant Biology
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A family of conserved bacterial effectors inhibits salicylic acid-mediated basal immunity and promotes disease necrosis in Arabidopsis. DebRoy S, et al. (2004) Proceedings of the National Academy of Sciences USA
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A Pseudomonas syringae type III effector suppresses cell wall-based extracellular defense in susceptible Arabidopsis plants. Hauck P, et al. (2003) Proceedings of the National Academy of Sciences USA
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Role of the Hrp pilus in type III secretion in Pseudomonas syringae. Jin Q-L. and He SY. (2001) Science
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The Arabidopsis thaliana-Pseudomonas syringae Interaction. Katagiri F, et al. (2002) The Arabidopsis Book, eds. C.R. Somerville and E.M. Meyerowitz, American Society of Plant Biologists, Rockville, MD.
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The gene coding for the structural protein of the Hrp pilus is required for type III secretion of Hrp and Avr proteins in Pseudomonas syringae pv. tomato. Wei W, et al. (2000) Proceedings of the National Academy of Sciences USA
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Hrp pilus: An hrp-dependent bacterial surface appendage produced by Pseudomonas syringae pv. tomato DC3000. Roine E, et al. (1997) Proceedings of the National Academy of Sciences USA
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Harpin, elicitor of the hypersensitive response produced by the plant pathogen Erwinia amylovora. Wei Z-M., et al. (1992) Science
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Cloned out genes from Erwinia chrysanthemi EC16 enable Escherichia coli strains to selectively secrete a diverse family of heterologous proteins to its milieu. He SY, et al. (1991) Proceedings of the National Academy of Sciences USA
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Patents
US 20170215351 A1
Methods and Apparatus for Gnotobiotic Plant Growth (2017) James Kremer, James Tiedje and Sheng Yang He
US PPA 62/413850
Structurally modified COI1 (2016) Sheng Yang He, Li Zhang et al.
US 8058507 B2
HOPM1 mediated disease resistance to Pseudomonas syringae in Arabidopsis (2011) Sheng Yang He and Kinya Nomura
US 9068192 B2
Compositions and Methods for Conversion of Aldehydes to Alkanes (2011) Weiqing Zeng and Sheng Yang He
US 6342654 B1
Broad-spectrum disease resistance conferred by expression of the Pseudomonas syringae hrmA gene in plants (2001) Qingshun Li, Songhai Shen, Arthur Hunt and Sheng Yang He
US 5849868 A
Elicitor of the hypersensitive response in plants (1998) Steve Beer et al.
This patent has led to the development of the disease control product “MESSENGERTM” sold by Eden Bioscience Corp.
US 5708139 A
Pseudomonas syringae pv. syringae HrpZ gene (1997) Alan Collmer and Sheng Yang He